Nucleotides in veterinary medicine Fundamental for over 10 pathologies

Where are the nucleotides found?

Nucleotides are found mostly in yeast.

Why it is important to integrate the diet of dogs and cats with Nucleotides

Nucleotides are particularly necessary for the development of tissues with a high rate of cell replication, such as the tissues of the immune and digestive systems, they act as growth factors on intestinal cells, increase the weight of the intestinal mucosa and the activity of enzymes located at the level of the brush border (maltase, sucrase, and lactase), promote the growth of intestinal microbial flora, in particular Lactobacilli and Bifidobacteria.

Their supplementation is necessary in case of

• Inflammatory bowel disease (IBD)
• Acute and chronic diarrhea
• Prolonged fasting
• Enter yourself
• leishmaniasis
• Anemia
• Hemorrhagic diarrhea
• Parasitosis
• Convalescence from infectious processes
• Intestinal mucosa restoration
• Immunosuppressed animals
• liver disease
• Anorexia
• Neoplastic cachexia
• Weaning and growth of puppies

Nucleotides for the integrity of the intestinal mucosa and for the immune system

Nucleotides also show a direct effect on maintaining the integrity of the intestinal mucosa, improving cell-mediated and humoral immunity.

• They accelerate the production of T-cell antibodies
• They help fight infections
• They promote the phagocytic activity of macrophages and the interaction of macrophages with T cells
• They improve the digestive and immune response afterward chemotherapy

NUCLEOVISLB® with Nucleotides concentrated in the only specific species composition for dogs

Why choose NUCLEOVISLB® with Nucleoforce Dogs ™ as a supplement to the dog’s diet? is a concentrated blend based on carefully selected extracts to support the dog’s gastrointestinal immune system?

The supplement of nucleotides in the diet favors a reduction of the consequences of stress

NUCLEOVIS LB® is useful for puppies during weaning, moles older dogs and in convalescence, they promote normal digestive activity and physiological immune response. In the sport dog, NUCLEOVIS LB® supports stressful activity by improving the post-training recovery process.

Nucleotides are especially necessary for the development of tissues with a high replication rate cellular, as occurs in the immune and digestive systems.

NUCLEOVIS LB® MAIN EFFECTS ON THE INTESTINE

• Acceleration of the growth and differentiation of the intestine itself
• Increase in the length of the intestinal villi
• Increased activity of intestinal enzymes
• Accelerated healing after diarrhea and/or fasting

NUCLEOVIS LB® ON THE IMMUNE SYSTEM

Effects on humoral immunity:

• Acceleration of antibody production by T lymphocytes
• Acceleration of resistance to bacterial and viral infections
• Decreased mortality in infected animals

Effects on cellular immunity:

• Increase in the activity of natural killer cells and in the production of interleukin-2
• Increase in the number of macrophages
• Increased phagocytic activity of macrophages
• Increased resistance to pathogens
• Acceleration of medullary and peripheral proliferation of neutrophils

MAIN EFFECTS OF ADDING NUCLEOVIS LB® TO A DOG’S DIET

In puppies and young dogs, nucleotides contribute to the natural growth process during weaning and rearing.

• Elderly animals: promote better digestive and immune activity.
• Animals with professional sporting activity: they support during competitive and work performance by contributing to the recovery process.
• Immunosuppressed or convalescent animals: they improve the digestive and immune response after the chemotherapy.
• Animals in different conditions stress: change of power supply, modifications of the environment.
• Lactating females

The cells that most need nucleotides are those with the fastest replication, such as those of the intestine, the immune system and the tissues of growing animals.

NUCLEOVIS LB® complementary feed is particularly suitable for supporting the physiological intestinal well-being with Nucleotides concentrated in the only species-specific composition for dogs: Nucleoforce Dogs ™

The cells that most need nucleotides are those with the fastest replication, such as those of the intestine, the immune system and the tissues of growing animals.

Nucleotides are essential for the proper functioning of the immune system, for cell repair, after illness, and to help prevent disease. They are needed to repair and replace cells.

Dietary nucleotides and the related compound of hexose active against leishmaniasis

A recent study on dogs with leishmaniasis who received methylglucamine antimoniate for 28 days showed that the biannual administration of a food supplement containing nucleotides more AHCC achieves an efficacy similar to that of allopurinol.

Impromune dog cat what is it for?

• A paper published by Veterinary Parasitology has shown that Impromune it is as efficient as standard allopurinol treatment.

IMPROMUNE® is a food supplement recommended for dogs and cats to strengthen their immune systems and to enhance any innate or adaptive response. Nucleoforce® is a specific formulation of Nucleotides developed after studying the specific needs of different mammal species. Nucleotides are semi-essential immune nutrients that, when taken orally, contribute to the proper development of the immune system.

Nucleoforce® regulates the phagocytic activity of macrophages and the interaction between them and T lymphocytes. It also regulates the maturation, proliferation, and activity of T lymphocytes. AHCC is an extract from the mycelium of Lentinus edodes, which regulates the activity of NK cells, as well as macrophage proliferation and T lymphocyte differentiation into Th1. Several studies have shown that in combination, Nucleoforce® e AHCC they have a synergistic effect that acts on innate and adaptive responses.

Romano V., et al .: Dietary nucleotides and immune status of puppies. J. Anim. Nutr. 2007.91: 158-162.

Segarra, Sergi, et al. “Randomized, allopurinol-controlled trial of the effects of dietary nucleotides and active hexose correlated compound in the treatment of canine leishmaniosis.” Veterinary parasitology 239 (2017): 50-56

Carver, Jane D. “Dietary nucleotides: cellular immune, intestinal and hepatic system effects.” The Journal of nutrition 124.suppl_1 (1994): 144S-148S.

Van, CT Buren, et al. “Dietary nucleotides, a requirement for helper/inducer T lymphocytes.” Transplantation 40.6 (1985): 694-697.

Uauy, Ricardo. “Nonimmune system responses to dietary nucleotides.” The Journal of nutrition 124.suppl_1 (1994): 157S-159S.

Gil, A. (2002). Modulation of the immune response mediated by dietary nucleotides. European Journal of Clinical Nutrition, 56 (S3), S1.

Carver, JD “Dietary nucleotides: effects on the immune and gastrointestinal systems.” Acta Paediatrica 88 (1999): 83-88.

Pizzini, Roland P., et al. “Dietary nucleotides reverse malnutrition and starvation-induced immunosuppression.” Archives of Surgery 125.1 (1990): 86-90.

Grimble, George K., and Olwyn M. Westwood. “Nucleotides as immunomodulators in clinical nutrition.” Current Opinion in Clinical Nutrition & Metabolic Care 4.1 (2001): 57-64.

Disclaimer: The contents are for informational purposes only and in no case can they constitute the prescription of treatment or replace the specialist visit or the direct relationship with your veterinarian/doctor. All the information reported here derives from Bibliographic sources, personal experiences, and clinical studies in the public domain. The information disseminated on the site is published after careful checks of the sources, chosen with care and updated and official as far as possible. All information on special diets and food supplements for pets is for informational purposes. This information serves as a general guideline, cannot be applied to all pets or considered as an alternative to professional advice. In These Pages are inserted and presented alternative therapy and homeopathic remedies of efficacy not scientifically validated and without approved therapeutic indications. The products are not intended as a substitute for a varied and balanced diet and must be used as part of a healthy lifestyle.